New insights into the pathomechanism of cyclic neutropenia
نویسندگان
چکیده
منابع مشابه
New insights into the genetics of congenital neutropenia.
Several congenital disorders may cause neutropenia. The recent advances in the field of molecular biology have facilitated our knowledge concerning pathophysiological mechanisms leading to these disorders. The molecular basis of disorders with defective myelopoiesis (severe congenital neutropenia and cyclic neutropenia) and disorders due to defective RNA processing (Shwachman Diamond syndrome a...
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متن کاملCyclic neutropenia.
Cyclic neutropenia is a rare hematologic disorder, characterized by repetitive episodes of fever, mouth ulcers, and infections attributable to recurrent severe neutropenia. Fluctuations in blood cells are due to oscillatory production of cells by the bone marrow. Recent genetic, molecular, and cellular studies have shown that autosomal-dominant cyclic neutropenia and sporadic cases of this dise...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 2020
ISSN: 0077-8923,1749-6632
DOI: 10.1111/nyas.14309